Duane Loh


Since his time at Cornell, Duane has been developing algorithms to probe nanoscale phenomena by examining their signatures, which are hidden in noisy, incomplete and heterogeneous X-ray diffractive datasets.

Structural complexity in aerosol soot: Scale-invariant random processes drive the growth and aggregation of these aerosols, which results in fractal-like geometrical properties.

These algorithms were applied during his postdoctoral appointment at SLAC National Accelerator Laboratory to investigate airborne aerosols, tiny viruses, paramagnetic aggregates, and supercooled water using X-ray free-electron lasers.

At NUS, Duane explores the physical, statistical and biological challenges encountered in electron microscopy and x-ray diffractive imaging to understand how we can extend our study and manipulation of mesoscale structure and dynamics.

Selected Publications

N. Duane Loh, et. al. “Multi-step nucleation of nanocrystals in aqueous solution”, Nature Chemistry 9, 77-82, 2017.

U. Anand, J. Lu, D. Loh, Z. Aabdin, and U. Mirsaidov, “Hydration Layer-mediated Pairwise Interaction of Nanoparticles” Nano Letters 16, 786 (2015).

J. A. Sellberg, C. Huang, T. A. McQueen, N. D. Loh, H. Laksmono, D. Schlesinger, R. G. Sierra, L. G. M. Pettersson, M. J. Bogan, A. Nilsson, et al. “Ultrafast X-ray probing of water structure below the homogeneous ice nucleation temperature” Nature 510, 381 (2014).

N. D. Loh, et al., “Sensing the wavefront of x-ray free-electron lasers using aerosol spheres” Opt. Express 21, 12385 (2013).

N. D. Loh, C. Y. Hampton, A. V Martin, D. Starodub, R. G. Sierra, A. Barty, M. J. Bogan et al. “Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight”. Nature. 486, 513–517 (2012).


2016-current: Assistant professor at the departments of Physics and Biological Sciences at NUS.

2013-2016: Lee Kuan Yew Postdoctoral Fellowship award at NUS.

2010-2010: Research fellow at SLAC National Accelerator Laboratory (Menlo Park, CA, USA).

2004-2010: Ph.D. in theoretical Physics at Cornell University (Ithaca, NY, USA).

2000-2004: B.Sc. in Physics at Harvey Mudd College (Claremont, CA, USA).