About CBIS

Our Mission

Founded by faculty from Biological Sciences, Chemistry, and Physics, the Centre for BioImaging Sciences’s (CBIS) research is focused on the science and application of biological imaging by light and electron microscopy and the development of computational and microscopy-based methods and technologies.

With an interdisciplinary emphasis on the mechanism of biological processes at the molecular, cell, and tissue levels, CBIS complements the development of advanced light microscopy technologies by the Optical Bioengineering Laboratory in the NUS Division of Bioengineering, the medical imaging research and applications in the Singapore Bioimaging Consortium, and the advanced confocal and super-resolution microscopes of the Mechanobiology Institute, Singapore.

Directors Message

Paul Matsudaira, Director, Centre for BioImaging Sciences

Through the centuries, discoveries have built on discoveries, and knowledge has built on knowledge. Technology has opened avenues of exploration never before conceived.

Then there is the present. We are living in an exciting time, when we have both the awareness and expertise to explore ever-expanding scales of knowledge about molecules and cells, and the technology to make it possible. In particular, advances in imaging have catalyzed advances in biology. At the NUS Centre for BioImaging Sciences, we are developing and applying novel imaging technologies to key problems in biology.

“At CBIS, we have the ability to find new answers as well as ask new questions that enhance our understanding of the most complex issues in biology.”

Recent advances in biology, chemistry, computer sciences, and physics – and the remarkable evolution of microscopes and computation – enable us to watch single molecules in action, create three-dimensional images of molecules over time, and observe them in live cells and tissues. Biomolecular imaging has not only gone far beyond its earlier capabilities, it has also surpassed other traditional methods of cellular research. Now we have the means to delve into systems-scale questions, observing many different molecules – and the structures they comprise – simultaneously and in real time.

We invite you to explore the Centre for BioImaging Sciences, and to join us in applying our tools, resources, and expertise to the microscopic mysteries that await discovery.

Paul Matsudaira
Director, Centre for BioImaging Sciences
Distinguished Professor, Department of Biological Sciences
Principal Investigator, Mechanobiology Institute, National University of Singapore