Duane Loh

Research

Dr Ne-Te Duane Loh, who is jointly sponsored by DBS and Physics has been selected for the prestigious Lee Kuan Yew Postdoctoral Fellowship award.

Duane earned his B.Sc. and Ph.D., both in Physics, from Harvey Mudd College and Cornell University respectively. Since his time at Cornell, Duane has been developing algorithms to probe nanoscale phenomena by examining their signatures, which are hidden in noisy, incomplete and heterogeneous X-ray diffractive datasets. These algorithms were applied during his postdoctoral appointment at SLAC National Accelerator Laboratory to investigate airborne aerosols, tiny viruses, paramagnetic aggregates, and supercooled water using X-ray free-electron lasers.

duaneLoh_structuralComplexitySM
Structural complexity in aerosol soot: Scale-invariant random processes drive the growth and aggregation of these aerosols, which results in fractal-like geometrical properties.

At NUS, Duane explores the physical, statistical and biological challenges encountered in electron microscopy and x-ray diffractive imaging to understand how we can extend our study and manipulation of mesoscopic structure and dynamics.

Selected Publications

Bonding Pathways of Gold Nanocrystals in Solution. Zainul Aabdin, Jingyu Lu, Xi Zhu, Utkarsh Anand, N Duane Loh, Haibin Su, and Utkur Mirsaidov. Nano Lett., 2014, 14 (11), pp 6639–6643
(DOI: 10.1021/nl5032919).

Experimental Observation of Bulk Liquid Water Structure in ‘No Man’s Land’. JA Selberg, C Huang, TA McQueen, ND Loh, H Laksmono, D Schlesinger, R Sierra, MJ Bogan, A Nilsson et al. Nature 510, 381–384 (2014).

Nanoparticle Dynamics in a Nanodroplet. J Lu, Z Aabdin, ND Loh, D Bhattacharya, U Mirsaidov. Nano Lett. 14, 2111–2115 (2014).

Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers. HJ Park, ND Loh et al.  Opt. Express. 21, 28729–28742 (2013).

A minimal view of single-particle imaging with X-ray lasers. ND Loh. Philosophical Transactions of the Royal Society B: Biological Sciences 369, 20130328–20130328 (2014).

2013 Probing the wavefront of x-ray free-electron lasers using aerosol spheres. ND Loh, D Starodub, A Barty, HN Chapman, MJ Bogan et al. Optics Express 21, 12385-12394 (2013).

Fractal Morphology, imaging and mass spectrometry of single aerosol particles in flight. ND Loh, CY Hampton, AV Martin, D Starodub, A Barty, MJ Bogan et al. Nature 486, 513–517 (2012).

Noise-robust coherent diffractive imaging with a single diffraction pattern. AV Martin, F Wang, ND Loh, MJ Bogan, HN Chapman et al. Optics Express 20, 16650 (2012).

Femtosecond dark-field imaging with an x-ray free electron laser. AV Martin, ND Loh, CY Hampton, MJ Bogan, HN Chapman et al. Optics Express 20(12), 13501 (2012).

Recovering magnetization distributions from their noisy diffraction data. ND Loh, S Flewett, S Eisebitt, V Elser. Phys Rev E 82, 061128 (2010) (weblink).

Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns. ND Loh, MJ Bogan, A Barty, V Elser, HN Chapman, et al. Phys Rev Lett. 104, 225501 (2010) (weblink)

A reconstruction algorithm for single-particle diffraction imaging experiments. ND Loh, V Elser. Phys Rev E 80 026705 (2009) (weblink).